Publications


Multistep Networks for Deformable Multimodal Medical Image Registration

30.01.2025

Strittmatter A, Zöllner FG. Multistep Networks for Deformable Multimodal Medical Image Registration. IEEE Access, 2024, 12, pp.82676-82692. DOI: 10.1109/ACCESS.2024.3412216 Publisher: IEEE Abstract: We proposed neural networks for deformable multimodal medical image registration that use multiple steps and varying resolutions. The networks were trained jointly in an unsupervised manner with Mutual Information and Gradient L2 loss.

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EAGLE: an edge-aware gradient localization enhanced loss for CT image reconstruction

30.01.2025

Yipeng Sun, Yixing Huang, Zeyu Yang, Linda-Sophie Schneider, Mareike Thies, Mingxuan Gu, Siyuan Mei, Siming Bayer, Frank G. Zöllner, and Andreas Maier “EAGLE: an edge-aware gradient localization enhanced loss for CT image reconstruction,” Journal of Medical Imaging 12(1), 014001 (22 January 2025). https://doi.org/10.1117/1.JMI.12.1.014001 Purpose We aim to enhance deep learning-based computed tomography (CT) image reconstructions.

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Comparing quantitative image parameters between animal and clinical CT-scanners: a translational phantom study analysis

05.06.2024

Vellala A, Mogler C, Haag F, Tollens F, Rudolf H, Pietsch F, Wängler C, Wängler B, Schoenberg SO, Froelich MF, Hertel A. Comparing quantitative image parameters between animal and clinical CT-scanners: a translational phantom study analysis. Front Med (Lausanne). 2024 Jun 5;11:1407235. doi: 10.3389/fmed.2024.1407235. Abstract Purpose: This study compares phantom-based variability of extracted radiomics features

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A rapid calibration pipeline for robotic percutaneous interventions – how a prototype learned to be accurate

27.05.2024

C. D. Wörnle, R. Lutz, L. Kuntz, J. Stallkamp, M. Siegfarth, Heidelberg University, Mannheim (DE) [ISCAS-LE-59-V].A rapid calibration pipeline for robotic percutaneous interventions – how a prototype learned to be accurate.CARS 2024—Computer Assisted Radiology and Surgery. Proceedings of the 38th International Congress and Exhibition. Barcelona, Spain, June 18–21, 2024. doi: 10.1007/s11548-024-03128-9

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Automated prognosis of renal function decline in ADPKD patients using deep learning

22.05.2024

Anish Raj, Fabian Tollens, Anna Caroli, Dominik Nörenberg, Frank G. Zöllner. Automated prognosis of renal function decline in ADPKD patients using deep learning. Zeitschrift für Medizinische Physik,. Volume 34, Issue 2, 2024, Pages 330-342. doi:10.1016/j.zemedi.2023.08.001 Abstract An accurate prognosis of renal function decline in Autosomal Dominant Polycystic Kidney Disease (ADPKD) is crucial for early intervention.

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Validation of the standardization framework SSTR-RADS 1.0 for neuroendocrine tumors using the novel SSTR‑targeting peptide [18F]SiTATE

20.05.2024

Ebner R, Lohse A, Fabritius MP, Rübenthaler J, Wängler C, Wängler B, Schirrmacher R, Völter F, Schmid HP, Unterrainer LM, Öcal O, Hinterberger A, Spitzweg C, Auernhammer CJ, Geyer T, Ricke J, Bartenstein P, Holzgreve A, Grawe F. Validation of the standardization framework SSTR-RADS 1.0 for neuroendocrine tumors using the novel SSTR‑targeting peptide [18F]SiTATE. Eur

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Characterization of Microwave Generator Energy and Ablation Volumes following Transarterial Embolization in an In Vivo Porcine Liver Model

14.05.2024

Sparks H, Rink JS, Ramakrishnan A, Sung K, Ni J, Lu DSK, Raman SS, Lee EW, Chiang J. Characterization of Microwave Generator Energy and Ablation Volumes following Transarterial Embolization in an In Vivo Porcine Liver Model. J Vasc Interv Radiol. 2024 May 14:S1051-0443(24)00339-7. doi: 10.1016/j.jvir.2024.05.005. Abstract Purpose: To characterize the relationship between ablation zone volume

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Development of Novel Hydraulic 3D Printed Actuator Using Electrorheological Fluid for Robotic Endoscopy

29.04.2024

Sadi, F.; Holthausen, J.; Stallkamp, J.; Siegfarth, M. Development of Novel Hydraulic 3D Printed Actuator Using Electrorheological Fluid for Robotic Endoscopy. Actuators 2024, 13, 119. https://doi.org/10.3390/act13040119 Abstract Endoscopy has made a significant and noteworthy contribution to the field of medical science and technology. Nevertheless, its potential remains constrained due to the limited availability of rigid

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Imaging-based characterization of tumoral heterogeneity for personalized cancer treatment

29.04.2024

Haag F, Hertel A, Tharmaseelan H, Kuru M, Haselmann V, Brochhausen C, Schönberg SO, Froelich MF. Imaging-based characterization of tumoral heterogeneity for personalized cancer treatment. Rofo. 2024 Mar;196(3):262-272. English. doi: 10.1055/a-2175-4622. Epub 2023 Nov 9. Erratum in: Rofo. 2023 Dec 28;: PMID: 37944935. Abstract With personalized tumor therapy, understanding and addressing the heterogeneity of malignant

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Silicon–Fluoride Acceptors (SiFA) for 18F-Radiolabeling: From Bench to Bedside

14.02.2024

Gower-Fry L, Wängler C, Bartenstein P, Beyer L, Lindner S, Jurkschat K, Wängler B, Bailey JJ, Schirrmacher R. (2024) Silicon-FluorideAcceptors (SiFA) for 18F-Radiolabeling: From Bench to Bedside. Methods Mol Biol., 2729, 29-43. https://doi.org/10.1007/978-1-0716-3499-8_3 Abstract Fluorine-18 (18F) is undoubtedly one of the most frequently applied radionuclides for the development of new radiotracers for positron emission tomography

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