Publications


Multiple direction needle-path planning and inverse dose optimization for robotic low-dose rate brachytherapy

15.11.2021

Philipp Aumüller, Andreas Rothfuss, Martin Polednik, Yasser Abo-Madyan, Michael Ehmann, Frank A Giordano, Sven Clausen Z Med Phys. 2021 Aug 6;S0939-3889(21)00061-1. doi: 10.1016/j.zemedi.2021.06.003 Online ahead of print. PMID: 34373188 DOI: 10.1016/j.zemedi.2021.06.003 Abstract Purpose: Robotic systems to assist needle placements for low-dose rate brachytherapy enable conformal dose planning only restricted to path planning around risk structures. We report a treatment planning system

... read more

Spatial Probabilistic Mapping of Metabolite Ensembles in Mass Spectrometry Imaging

28.10.2021

Sammour, Denis Abu, et al. “Spatial Probabilistic Mapping of Metabolite Ensembles in Mass Spectrometry Imaging.” bioRxiv (2021). https://doi.org/10.1101/2021.10.27.466114 Posted: 28 October 2021 Abstract Mass spectrometry imaging (MSI) vows to enable simultaneous spatially-resolved investigation of hundreds of metabolites in tissue sections, but it still relies on poorly defined ion images for data interpretation. Here, we outline moleculaR, a

... read more

An anthropomorphic pelvis phantom for MR-guided prostate interventions

15.10.2021

D. Bauer, A. Adlung, I. Brumer, A. Golla, T. Russ, E. Oelschlegel, F. Tollens, S. Clausen, P. Aumüller, L. Schad, D. Nörenberg and F. Zöllner. An anthropomorphic pelvis phantom for MR-guided prostate interventions.Magn Reson Med, 2022, 87 (3), pp.1605-1612. First published: 15 October 2021 https://doi.org/10.1002/mrm.29043 Abstract Purpose To design and manufacture a pelvis phantom for magnetic

... read more

Robotic Assistance System for Cone-Beam Computed Tomography-Guided Percutaneous Needle Placement

19.08.2021

Kostrzewa, M., Rothfuss, A., Pätz, T. et al. Robotic Assistance System for Cone-Beam Computed Tomography-Guided Percutaneous Needle Placement. Cardiovasc Intervent Radiol 45, 62–68 (2022). https://doi.org/10.1007/s00270-021-02938-7 Abstract Purpose The study aimed to evaluate a new robotic assistance system (RAS) for needle placement in combination with a multi-axis C-arm angiography system for cone-beam computed tomography (CBCT) in

... read more

MRT-gestützte minimal-invasive Therapie des Prostatakarzinoms

12.07.2021

Tollens, F., Westhoff, N., von Hardenberg, J. et al. MRT-gestützte minimal-invasive Therapie des Prostatakarzinoms. Radiologe 61, 829–838 (2021). Published 12 July 2021 https://doi.org/10.1007 Zusammenfassung Klinisches/methodisches Problem Die multiparametrische Magnetresonanztomographie (mpMRT) der Prostata ist als entscheidender Bestandteil in der Früherkennung und Ausbreitungsdiagnostik des primären Prostatakarzinoms etabliert. Radiologische Standardverfahren Bildgestützte Biopsieverfahren, wie die MRT-Ultraschall-Fusionsbiopsie, erlauben nicht nur

... read more

Design, Synthesis, In Vitro and In Vivo Evaluation of Heterobivalent SiFAlin-Modified Peptidic Radioligands Targeting Both Integrin αvβ3 and the MC1 Receptor—Suitable for the Specific Visualization of Melanomas?

07.06.2021

Cheng, X.; Hübner, R.; von Kiedrowski, V.; Fricker, G.; Schirrmacher, R.; Wängler, C.; Wängler, B. Design, Synthesis, In Vitro and In Vivo Evaluation of Heterobivalent SiFAlin-Modified Peptidic Radioligands Targeting Both Integrin αvβ3 and the MC1 Receptor—Suitable for the Specific Visualization of Melanomas? Pharmaceuticals 2021, 14, 547. https://doi.org/10.3390/ph14060547 Abstract Combining two peptides addressing two different receptors

... read more

Rapid brain structure and tumour margin detection on whole frozen tissue sections by fast multiphotometric mid-infrared scanning

28.05.2021

Kümmel, T., van Marwick, B., Rittel, M. et al. Rapid brain structure and tumour margin detection on whole frozen tissue sections by fast multiphotometric mid-infrared scanning. Sci Rep 11, 11307 (2021). https://doi.org/10.1038/s41598-021-90777-4 Published: 28 May 2021 Abstract Frozen section analysis is a frequently used method for examination of tissue samples, especially for tumour detection. In

... read more

Kidney Segmentation in Renal Magnetic Resonance Imaging – Current Status and Prospects

20.05.2021

F. G. Zöllner et al., “Kidney Segmentation in Renal Magnetic Resonance Imaging – Current Status and Prospects,” in IEEE Access, vol. 9, pp. 71577-71605, 2021, doi: 10.1109/ACCESS.2021.3078430. Abstract Magnetic resonance imaging has achieved an increasingly important role in the clinical work-up of renal diseases such chronic kidney disease (CKD). A large panel of parameters have

... read more

Convolutional Neural Network Ensemble Segmentation With Ratio-Based Sampling for the Arteries and Veins in Abdominal CT Scans

02.05.2021

A. -K. Golla et al., “Convolutional Neural Network Ensemble Segmentation With Ratio-Based Sampling for the Arteries and Veins in Abdominal CT Scans,” in IEEE Transactions on Biomedical Engineering, vol. 68, no. 5, pp. 1518-1526, May 2021, doi: 10.1109/TBME.2020.3042640. Abstract Objective: Three-dimensional (3D) blood vessel structure information is important for diagnosis and treatment in various clinical

... read more

Generation of annotated multimodal ground truth datasets for abdominal medical image registration

02.05.2021

Bauer, D.F., Russ, T., Waldkirch, B.I. et al. Generation of annotated multimodal ground truth datasets for abdominal medical image registration. Int J CARS (2021). https://doi.org/10.1007/s11548-021-02372-7 Abstract Purpose Sparsity of annotated data is a major limitation in medical image processing tasks such as registration. Registered multimodal image data are essential for the diagnosis of medical conditions

... read more