Publikationen


pyM2aia: Python interface for mass spectrometry imaging with focus on deep learning

05.03.2024

Cordes, J., Enzlein, T., Hopf, C., & Wolf, I. (2024). pyM2aia: Python interface for mass spectrometry imaging with focus on deep learning. Bioinformatics, 40(3), btae133. https://doi.org/10.1093/bioinformatics/btae133 Abstract Summary Python is the most commonly used language for deep learning (DL). Existing Python packages for mass spectrometry imaging (MSI) data are not optimized for DL tasks. We, therefore, introduce

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Silicon–Fluoride Acceptors (SiFA) for 18F-Radiolabeling: From Bench to Bedside

14.02.2024

Gower-Fry L, Wängler C, Bartenstein P, Beyer L, Lindner S, Jurkschat K, Wängler B, Bailey JJ, Schirrmacher R. (2024) Silicon-FluorideAcceptors (SiFA) for 18F-Radiolabeling: From Bench to Bedside. Methods Mol Biol., 2729, 29-43. https://doi.org/10.1007/978-1-0716-3499-8_3 Abstract Fluorine-18 (18F) is undoubtedly one of the most frequently applied radionuclides for the development of new radiotracers for positron emission tomography

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Computed tomography imaging phenotypes of hepatoblastoma identified from radiomics signatures are associated with the efficacy of neoadjuvant chemotherapy

30.01.2024

Chen Y, Froelich MF, Tharmaseelan H, Jiang H, Wang Y, Li H, Tao M, Gao Y, Wang J, Liu J, Schoenberg SO, Feng S, Weis M. Computed tomography imaging phenotypes of hepatoblastoma identified from radiomics signatures are associated with the efficacy of neoadjuvant chemotherapy. Pediatr Radiol. 2024;54(1):58-67. (0) PMID: 37982901 PMCID: PMC10776468 DOI: 10.1007/s00247-023-05793-5 Abstract

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Photon-counting computed tomography – clinical application in oncological, cardiovascular, and pediatric radiology

11.01.2024

Hagen F, Soschynski M, Weis M, Hagar MT, Krumm P, Ayx I, Taron J, Krauss T, Hein M, Ruile P, von Zur Muehlen C, Schlett CL, Neubauer J, Tsiflikas I, Russe MF, Arnold P, Faby S, Froelich MF, Weiß J, Stein T, Overhoff D, Bongers M, Nikolaou K, Schönberg SO, Bamberg F, Horger M. Photon-counting

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Radiosynthesis of stable 198Au-nanoparticles by neutron activation of αvβ3-specific AuNPs for therapy of tumor angiogenesis

30.11.2023

Davarci G, Wängler C, Eberhardt K, Geppert C, Schirrmacher R, Freudenberg R, Pretze M, Wängler B (2023) Radiosynthesis of stable 198Au-nanoparticles by neutron activation of αvβ3-specific AuNPs for therapy of tumor angiogenesis. Pharmaceuticals, 16(12), 1670. DOI: 10.3390/ph16121670. Abstract This paper reports on the development of stable tumor-specific gold nanoparticles (AuNPs) activated by neutron irradiation as

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CycloSiFA: The Next Generation of Silicon-Based Fluoride Acceptors for Positron Emission Tomography (PET)

18.10.2023

Mawick M, Jaworski C, Bittermann J, Iovkova L, Pu Y, Wängler C, Wängler B, Jurkschat K, Krause N, Schirrmacher R (2023) CycloSiFA: The Next Generation of Silicon-Based Fluoride Acceptors for Positron Emission Tomography (PET). Angewandte Chemie International Edition, 62(50), e202309002. DOI: 10.1002/anie.202309002. Graphical Abstract Cyclic azasilole derivatives undergo ring-opening with 18F– anions under mild conditions

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Good practices for the automated production of 18F-SiFA radiopharmaceuticals

11.10.2023

Blok S, Wängler C, Bartenstein P, Schirrmacher R, Lindner S (2023) Good practices for the automated production of 18F-SiFA radiopharmaceuticals. EJNMMI Radiopharmacy and Chemistry, 8(1), 25. DOI: 10.1186/s41181-023-00215-1. Abstract Background The positron emitting isotope fluorine-18 (18F) possesses almost ideal physicochemical properties for the development of radiotracers for diagnostic molecular imaging employing positron emission tomography (PET).

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User-centric explainability in healthcare: A knowledge-level perspective of informed machine learning

15.08.2023

L. Oberste and A. Heinzl, „User-Centric Explainability in Healthcare: A Knowledge-Level Perspective of Informed Machine Learning,“ in IEEE Transactions on Artificial Intelligence, vol. 4, no. 4, pp. 840-857, Aug. 2023, doi: 10.1109/TAI.2022.3227225 Impact Statement: The majority of investigations of the explainability challenge are being conducted from a developer-oriented focus, typically summarizing end-users based on their

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Feature-Oriented CBCT Self-Calibration Parameter Estimator for Arbitrary Trajectories: FORCAST-EST

11.08.2023

Tönnes, C.; Zöllner, F.G. Feature-Oriented CBCT Self-Calibration Parameter Estimator for Arbitrary Trajectories: FORCAST-EST. Appl. Sci. 2023, 13, 9179. https://doi.org/10.3390/app13169179 Published: 11 August 2023 Abstract Background: For the reconstruction of Cone-Beam CT volumes, the exact position of each projection is needed; however, in some situations, this information is missing. Purpose: The development of a self-calibration algorithm

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Comparison of synthetic dataset generation methods for medical intervention rooms using medical clothing detection as an example

02.08.2023

Schülein, P., Teufel, H., Vorpahl, R. et al. Comparison of synthetic dataset generation methods for medical intervention rooms using medical clothing detection as an example. J Image Video Proc. 2023, 12 (2023). doi: 10.1186/s13640-023-00612-1. Abstract Purpose: The availability of real data from areas with high privacy requirements, suchas the medical intervention space is low and

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